Symbol
Name
ID

Krit1
KRIT1, ankyrin repeat containing
MGI:1930618

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Intracranial hemorrhage	Cerebral cavernous malformation	Hepatic vascular malformations	Retinal vascular malformation
Disease(s) Associated with KRIT1
cerebral cavernous malformation 1

Mouse Phenotypes

abnormal blood vessel morphology

abnormal artery morphology

abnormal dorsal aorta morphology

abnormal intersomitic artery morphology

abnormal pharyngeal arch artery morphology

pharyngeal arch artery stenosis

dilated aorta

abnormal brain vasculature morphology

abnormal retina vasculature morphology

abnormal vascular development

abnormal venule morphology

dilated vasculature

abnormal myocardial trabeculae morphology

thin myocardium

abnormal heart development

decreased cardiac jelly amount

abnormal heart looping

abnormal heart morphology

dilated heart atrium

enlarged heart

dilated heart ventricle

abnormal pericardium morphology

abnormal blood circulation

abnormal blood vessel physiology

abnormal vascular endothelial cell physiology

telangiectasia

Availability

Mouse Genotype

Krit1^{tm1.1(KOMP)Vlcg}/Krit1^{tm1.1(KOMP)Vlcg}

Krit1^tm1Dmar/Krit1^tm1Dmar

Krit1^{tm1.1(KOMP)Vlcg}/Krit1⁺

Krit1^tm1Arte/Krit1^tm1Arte
Tg(Cdh5-cre/ERT2)1Rha/0 (conditional)

Krit1^tm1Kwhi/Krit1^tm1Kwhi
Tg(Cdh5-cre/ERT2)1Rha/0 (conditional)

Krit1^tm1Kwhi/Krit1^tm1Kwhi
Nfatc1^tm1.1(cre)Bz/Nfatc1⁺ (conditional)

Krit1^tm1Kwhi/Krit1^tm1.1Kwhi
Tg(Tek-cre)1Ywa/0 (conditional)

Krit1^tm1Kwhi/Krit1^tm1.1Kwhi
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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